Transform Your R&D Through Strategic Platform Technology

Informatics, Cloud Architecture and Computational Biology Consulting

Helping biotech companies build scalable, regulatory-compliant data platforms and AI-powered workflows that accelerate discovery through clinical development.

StackBio represents building the complete technology stack—from data infrastructure and cloud architecture through computational workflows and AI integration—that enables modern biotechnology.

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About

Strategic R&D Executive Driving Digital Transformation in Life Sciences

Michael Dinsmore brings over 20 years of specialized expertise in building enterprise-scale computational biology and informatics platforms for biotech and genomics research organizations.

Most recently as VP of Platform Technology at Editas Medicine, Michael led cross-functional teams of 25+ across Computational Biology, Informatics, Sequencing, Screening and Delivery & Editing. He architected cloud-native AWS infrastructure, established AI/ML governance frameworks, and enabled three IND submissions through strategic technology investments achieving 5x efficiency gains with a $5M+ portfolio.

Prior to Editas, Michael spent 13 years at the Broad Institute of MIT and Harvard, managing software engineering teams building genetics research platforms supporting major genomics initiatives including GTEx, eMERGE, and HapMap, including CLIA-certified clinical sequencing portals.

With deep expertise in regulatory compliance (21 CFR Part 11, GxP, CLIA), cloud architecture, and AI/ML integration, Michael helps organizations navigate the complex intersection of scientific innovation, operational scalability, and regulatory requirements.

25+

Years Experience

IND Submissions Enabled

Efficiency Gains Delivered

$5M+

Technology Portfolio Managed

Services

Comprehensive platform technology and informatics consulting for biotech R&D

📊

Enterprise Informatics Platforms

LIMS, ELN, and data management systems for regulated environments

Benchling deployment & integration
LIMS/ELN implementation
Custom workflow automation
Laboratory system integration
Real-time analytics dashboards

☁️

Cloud Architecture & Data Platforms

AWS-native infrastructure for scientific computing at scale

Cloud-first migration strategy
Data lake architecture (S3, Athena, RDS)
Infrastructure-as-Code (CDK, CloudFormation)
CI/CD pipeline development
Cost optimization & security

🤖

AI/ML Strategy & Integration

Strategic roadmaps for ML and LLM adoption in scientific workflows

ML model development & deployment
LLM integration for documentation
AI governance frameworks
Predictive modeling pipelines
Data-driven discovery platforms

🎯

Strategic Technology Leadership

Technology roadmapping and organizational transformation

Platform strategy development
Team building & mentorship
Vendor evaluation & management
Budget planning & optimization
Digital transformation initiatives

🧬

Computational Biology & NGS Pipelines

Design and implementation of scalable sequencing and analysis workflows

End-to-end NGS pipeline architecture
Automated quality control & reporting
Multi-program parallel execution
Custom bioinformatics workflows
Target identification platforms

⚖️

Regulatory Compliance & Validation

GxP-compliant systems supporting IND submissions and clinical operations

21 CFR Part 11 compliance
GxP/GMP validation
CLIA certification support
IND documentation systems
Quality system integration

Experience Highlights

Building platforms that transform R&D operations

Vice President, Platform Technology

Editas Medicine, Inc.

January 2023 - October 2025

Led 25+ person organization across Computational Biology, Informatics, Sequencing, Screening, and Delivery & Editing
Enabled three IND submissions through specialized clinical operations tooling and data analysis platforms
Architected AI/ML roadmap with cross-functional governance spanning legal, ethics, and security
Managed $5M+ annual technology budget optimizing cloud infrastructure and automation investments
Established enterprise data governance ensuring regulatory compliance (21 CFR Part 11, GxP)

Associate Director / Director / Senior Director, Informatics

Editas Medicine, Inc.

May 2016 - January 2023

Built informatics team from zero through 7-year platform transformation
Architected cloud-first AWS migration modernizing legacy infrastructure with regulatory compliance
Engineered automated sequencing pipeline achieving 5x throughput increase
Led enterprise Benchling deployment for iNK cell therapy program with validated regulatory rigor
Designed AWS data lake architecture supporting large-scale analytics with Tableau integration

Group Leader, Software Engineering Manager

Broad Institute of MIT and Harvard

November 2003 - May 2016

Managed engineering team building genetics research platforms supporting projects including GTEx, eMERGE, CARe, and HapMap
Led informatics development for CLIA-certified clinical sequencing portal
Developed SNP genotyping applications with sample tracking and quality metrics
Drove division-wide adoption of open-source technology stack reducing licensing costs
Delivered technical presentations at Harvard Medical School, MGH, Dana-Farber, and Yale

Technical Expertise

Cloud & Infrastructure

AWS (Lambda, Batch, S3, Athena, ECS, RDS, Step Functions)
Infrastructure-as-Code (CDK, CloudFormation)
Data Lakes & Analytics Platforms
CI/CD Pipelines
Enterprise Data Governance

Scientific Platforms

Benchling
LIMS/ELN Systems
NGS Sequencing Pipelines
Illumina Platforms
Tableau & Analytics

AI/ML & Computational Biology

LLM Integration & Governance
Predictive Modeling
Bioinformatics
ML Model Deployment
Data-Driven Discovery

Development & Tools

Python
Java / Enterprise Java
REST APIs
React
DevOps Practices

Regulatory & Compliance

21 CFR Part 11
GxP & GMP
Validation & Qualification
CLIA Certification
IND Support & Documentation

Leadership

Strategic Planning
Digital Transformation
Cross-functional Teams (25+)
P&L Management ($5M+)
Vendor Management

Publications & Presentations

Presentations

When to Build with Benchling – Integrations and Innovation on the Benchling Platform

Benchtalk, September 2023

Mining large NGS datasets to support novel target discovery

Bioinformatics Strategy Meeting, November 2018

How Editas is Leveraging Benchling to Transform Genome Engineering R&D

Benchling User Meeting, October 2018

Using Modern Software to Transform R&D

BioIT World, May 2018

In the Loop

Festival of Genomics, September 2017

Building a Strategic R&D Advantage through an Integrated Informatics Platform

13th Laboratory Informatics Summit, December 2016

Publications

Harmonizing Clinical Sequencing and Interpretation for the eMERGE III Network

American Journal of Human Genetics, Volume 105, Issue 3, September 2019 (Collaborator)

Efficiency and Usability of a Near Field Communication-Enabled Tablet for Medication Administration

JMIR Mhealth Uhealth, 2(2): e26, April-June 2014

Improving Electronic Medication Administration and Reconciliation Using a Near Field Communication Enabled Mobile Device

American Medical Informatics Association (AMIA) Annual Symposium, November 2013

Advisory Roles

Technical Advisory Board, RFID Web Services WAN SIG W3C, MIT AUTO-ID Labs (2004-2012)